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A case of Meckel—Gruber syndrome was diagnosed by embryoscopy at 10 menstrual weeks, allowing for early termination of pregnancy. Post-mortem examination confirmed the presence of polydactyly and bilateral cystic lesions of the mesonephros and metanephros. Both the forming nephrons and the collecting ducts were involved in the formation of renal cysts.  相似文献   
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Organizational downsizing is often counterproductive and applied irrespective of past financial performance. The popularity of this tactic leads to the question of whether an executive's propensity to downsize is linked to characteristics such as uncertainty avoidance and risk tolerance, which can be examined at either an individual or societal level. Copyright © 2005 John Wiley & Sons, Ltd.  相似文献   
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Phosphorus (P) in agricultural ecosystems is an essential and limited element for plants and microorganisms. However, environmental problems caused by P accumulation as well as by P loss have become more and more serious. Oxygen isotopes of phosphate can trace the sources, migration, and transformation of P in agricultural soils. In order to use the isotopes of phosphate oxygen, appropriate extraction and purification methods for inorganic phosphate from soils are necessary. Here, we combined two different methods to analyze the oxygen isotopic composition of inorganic phosphate (δ18OP) from chemical fertilizers and different fractions (Milli-Q water, 0.5 mol L?1 NaHCO3 (pH = 8.5), 0.1 mol L?1 NaOH and 1 mol L?1 HCl) of agricultural soils from the Beijing area. The δ18OP results of the water extracts and NaHCO3 extracts in most samples were close to the calculated equilibrium value. These phenomena can be explained by rapid P cycling in soils and the influence of chemical fertilizers. The δ18OP value of the water extracts and NaHCO3 extracts in some soil samples below the equilibrium value may be caused by the hydrolysis of organic P fractions mediated by extracellular enzymes. The δ18OP values of the NaOH extracts were above the calculated equilibrium value reflecting the balance state between microbial uptake of phosphate and the release of intracellular phosphate back to the soil. The HCl extracts with the lowest δ18OP values and highest phosphate concentrations indicated that the HCl fraction was affected by microbial activity. Hence, these δ18Op values likely reflected the oxygen isotopic values of the parent materials. The results suggested that phosphate oxygen isotope analyses could be an effective tool in order to trace phosphate sources, transformation processes, and its utilization by microorganisms in agricultural soils.  相似文献   
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When a group of users who share a common-pool resource through a system of licenses is exposed to the risk of shortage, there is a need to establish a sharing rule. Such sharing rule is likely to impact the individual decisions to self-insure, i.e., to rely on a secure but costly resource instead of the free but uncertain common-pool resource. We determine the optimal sharing rule and the optimal diversification between the common-pool resource and the safe resource as a function of the agents’ individual characteristics, the distribution of the common-pool resource availability, and the cost of the safe resource. We find that, for a group of agents with heterogenous risk preferences, a perfectly informed regulator can obtain the optimal diversification level by imposing a rationing rule which shares the resource between agents proportionally to their relative risk tolerance. We illustrate and interpret our results in the context of water management in France.  相似文献   
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Intensifying global trade will result in increased numbers of plant pest and pathogen species inadvertently being transported along with cargo. This paper examines current mechanisms for prevention and management of potential introductions of forest insect pests and pathogens in the European Union (EU). Current European legislation has not been found sufficient in preventing invasion, establishment and spread of pest and pathogen species within the EU. Costs associated with future invasions are difficult to estimate but past invasions have led to negative economic impacts in the invaded country. The challenge is combining free trade and free movement of products (within the EU) with protection against invasive pests and pathogens. Public awareness may mobilise the public for prevention and detection of potential invasions and, simultaneously, increase support for eradication and control measures. We recommend focus on commodities in addition to pathways, an approach within the EU using a centralised response unit and, critically, to engage the general public in the battle against establishment and spread of these harmful pests and pathogens.  相似文献   
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Environmental Economics and Policy Studies - While the EU is working toward the implementation of the world’s first Carbon Border Adjustment (CBA) Mechanism, a gap remains between the ways in...  相似文献   
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